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treatment hematology apml bowel differential differentiation gastroenterology hemophagocytic hhv8 hlh ibs inflammatory irritable kaposi kics kshv lymphohistiocytosis oncology rheumatology sarcoidosis
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... and Management ... adsorption onto cancer cells ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... pro-inflammatory cytokines ... Purtilo (XLP) Acquired ... #management #treatment
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... * Bloating not required ... intestinal epithelial cells ... #Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology: • Cytokine ... Release from blast cells ... Differentiation #Syndrome ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... tissue: Epithelioid cells ... → cytokines to ... #Management #Signs
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory Cytokine ... Syndrome (KICS) ... peripheral mononuclear cells ... 100 copies/ cells ... #diagnosis #management
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