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diagnosis activetb hematology neurology tb treatment tuberculosis als amyotrophic clinical differential hemeonc hemophagocytic hlh lateral leukostasis lymphohistiocytosis lysis myelitis ocular
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
90%) & develop latent ... tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
90%) & develop latent ... tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... TB #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... between nerve cells ... neurology #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Shafer's sign on Slit Lamp Ocular Examination Pigmented cells in the anterior vitreous, which is highly suggestive
Shafer's sign on ... Examination Pigmented cells ... Shafers #Schaffers #sign ... PhysicalExam #clinical #video ... ophthalmology #SlitLamp
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 Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Presentation • Common Signs ... Pathophysiology ... function of NK cells ... and CD8+ T cells
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