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causes hematology management nephrology algorithm brue cancer emergencies event gitelman hypokalemia lifethreatening mds monoclonal myelodysplasia myelodysplastic oncologic paraproteinemias pathophysiology rhabdomyolysis
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework ... of breath • Neurologic ... neutrophil count < 500 cells ... • Paraplegia (late
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm Cardiac: • Congenital Heart Disease •
) - Differential ... Metabolism • Reye's Syndrome ... Disturbances Neurologic ... #Causes #Peds # ... Pediatrics
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... Pinpoint-sized red spots ... blood count with differential ... #diagnosis #hematology ... #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... 5X ULN • AST/ALT ... AST declines > ALT ... kidney tubular cells
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... Thrombosis in vascular beds-renal ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Multinucleated giant cells ... affects the skin, neurologic ... , Elevated AST ALT
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... apical membrane of cells ... Hypocalciuria (spot ... ratio 0.5%) Differential ... #diagnosis #nephrology
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