17 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... diagnosis #management #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... Rhabdomyolysis, Critical ... stroke, tumor), LMN ... NMJ disorder (Myasthenia ... Diagnosis #causes #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
age 50 years in men ... Diagnosis: • Based on clinical ... antibodies - MuSK-positive ... - Improves clinical ... diagnosis #management #neurology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Her clinical exam ... such as cogan sign ... tumor, and always ask ... #PhysicalExam #clinical ... ophthalmology #neurology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... think about three clinical ... Neurogenic Ptosis - Neurologic ... change • Contact lens ... #Differential #
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... heavy metals), Critical ... Eaton Syndrome, Myasthenia ... Weakness #Causes #differential ... #diagnosis #neurology
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... Diagnosis Algorithm Clinical ... • Neurologic ... • Myasthenia ... Error • Cataract/Lens
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... cellular function Clinical ... EMG: LMN Signs in ... conditions listed in differential ... Lateral #Sclerosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia ... - Lack of UMN/LMN ... signs - Lack ... #Diagnosis #neurology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... mass and NO prior signs ... radiograph, may lean ... - **MSK rads ... Differential diagnosis