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diagnosis management causes gravis weakness ophthalmology algorithm amyotrophic arteritis clinical diplopia doublevision eyelid gca generalized giantcell lateral myelitis neuromuscular ocular
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Resp/Heme: CHF, valves ... stroke, tumor), LMN ... Polyneuropathy, ALS ... NMJ disorder (Myasthenia ... Diagnosis #causes #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
age 50 years in men ... antibodies - MuSK-positive ... • All patients ... be performed in all ... diagnosis #management #neurology
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... Myasthenia gravis ... cogan sign and ... tumor, and always ask ... ophthalmology #neurology
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 Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Motor Nerves: ALS ... Eaton Syndrome, Myasthenia ... Weakness #Causes #differential ... #diagnosis #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
signs in the limbs ... signs to determine ... EMG: LMN Signs in ... conditions listed in differential ... Lateral #Sclerosis #neurology
Diplopia - Double Vision - Differential Diagnosis Algorithm Clinical Pearls: • Diplopia is almost always binocular. •
Double Vision - Differential ... • Neurologic ... suggest a mass as ... • Myasthenia ... Error • Cataract/Lens
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia ... - Lack of UMN/LMN ... signs - Lack ... #Diagnosis #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... or sed rate): Value ... very remarkable w/differential ... and age/2 for men
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... arthralgia, arm/leg ... affects the skin, neurologic ... aneurysms can also
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