11 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... diagnosis #management #neurology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... such as cogan sign ... tumor, and always ask ... constitute a medical emergency ... ophthalmology #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... stroke, tumor), LMN ... NMJ disorder (Myasthenia ... Diagnosis #causes #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... age 50 years in men ... anti—muscle-specific kinase (MuSK ... antibodies - MuSK-positive ... diagnosis #management #neurology
An Algorithm for the Management of Seizures

The management of active seizures is algorithmic, starting with a
adjuncts and bag-valve ... mask if needed) ... continuous vital sign ... Algorithm #Management #Emergency ... #Neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... loss of normal leg ... Note: Surgical Emergency ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
saddle anesthesia. leg ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Postsynaptic: Myasthenia ... - Lack of UMN/LMN ... signs - Lack ... aminotransferases • Serology ... Differential #Diagnosis #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... or sed rate): Value ... and age/2 for men ... GCA #Temporal #Signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... over a five to ten-year ... • Bilateral signs ... Predictive of MS ... diagnosis #management #neurology