16 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... diagnosis #management #neurology
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
and Symptoms ... over time) • Weakness ... : • Straight leg ... Radiculopathy #MSK ... #symptoms #pathophysiology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... Resp/Heme: CHF, valves ... stroke, tumor), LMN ... NMJ disorder (Myasthenia ... Diagnosis #causes #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
age 50 years in men ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... diagnosis #management #neurology
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
more common in men ... pre-determined etiology Signs ... /Symptoms/Complications ... Antalgic gait - Weakness ... #msk #orthopedics
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Spasm, Cramping, Weakness ... Signs and symptoms ... objective evidence of neurologic ... vision, Diplopia, Weakness ... diagnosis #management #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... : • Weakness ( ... loss of normal leg ... CaudaEquina #Syndrome #MSK ... #signs
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... non-localized EOM weakness ... such as cogan sign ... tumor, and always ask ... ophthalmology #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
saddle anesthesia. leg ... weakness and ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Postsynaptic: Myasthenia ... - Lack of UMN/LMN ... signs - Lack ... aminotransferases • Serology ... Differential #Diagnosis #neurology