26 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... #Leser #Trélat # ... Trelat #LeserTrelat ... #PhysicalExam #clinical
Lelli's Test (Lever Sign) for ACL Injury

A fist is placed under the proximal 3rd of the
Lelli's Test (Lever ... #Lellis #Test #Lever ... cruciate #ligament #clinical
Glucagon: Bypassing β-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
pathophysiology and clinical ... beta-blocker overdose #Toxicology ... #Pharmacology #
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... Clinical presentation ... Hydroxybutyrate #GHB #Toxicology ... Diagnosis #Management #Pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level ... Sample trough level ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... metabolized in the liver ... #Clozapine #Toxicology ... Toxicity #Diagnosis #Pharmacology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Pathogenesis and clinical ... distally from the lesser ... femur (e. g. low level
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
cycle found in the liver ... presentation - Clinical ... LacticAcidosis #Toxicity #Toxicology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show ... Abs, and to a lesser