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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... blood #disorders #leukemia ... #hematology #oncology ... #diagnosis #CML ... #CLL #AML #Map
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... APML, CLL Acute ... ↓ LAP Score • CML ... -> AML: Blast crises ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Transform to DLBCL, PML ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
older 50-70 • Malignant ... involved) • No leukemic ... Malignancies (eg CML ... , ALL) • Solid ... NonHodgkins #comparison #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
chemosensitive malignancy ... Burkitt's lymphoma & ALL ... lymphoma & Acute leukemia ... (both ALL and AML ... Syndrome #TLS #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
for appropriate dosing ... #DOAC #VTE #Malignancy ... #Anticoagulation ... #Management #Hematology ... #Oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Usually myeloid leukemias ... Hypercalcemia of malignancy ... fluids (200–300 mL ... : - Seen with AML
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... (CML) • Felty ... progression to AML ... #oncology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
generally requires all ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... • Treatment algorithms ... Hydroxyurea + anticoagulation
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment algorithm ... acute myeloid leukemia ... (AML). ... cytopenias and AML ... #algorithm #hematology