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diagnosis differential hypokalemia management treatment alkalosis binders binding chloride comparison gitelman hypertension hyponatremia hypotonic k low medications metabolic pathophysiology pharmacology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... constipation, diarrhea, nausea ... ); nausea, vomiting ... of aspiration #Potassium ... #pharmacology #table
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... treated with IV potassium ... A urine K/Cr ratio ... • Diarrhea A urine ... #nephrology #low
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
(correction of hypokalemia ... Oral sodium loading ... test (with 24-h urine ... #Screening #Workup ... #table
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... the indicated causes ... sodium is typically ... and potassium acid ... #Algorithm #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Weakness - Dark urine ... hour with goal urine ... Monitor potassium ... #treatment #nephrology
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... correcting serum potassium ... continued in most cases ... #differential #algorithm ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... lysis) ± Urine ... only if no clear cause ... Elimination (see Table ... #nephrology #K
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypokalemic salt-losing ... thiazide-sensitive sodium ... (renal potassium ... Hypocalciuria (spot urine ... Syndrome #diagnosis #nephrology
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