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nephrology comparison diagnosis management pharmacology differential hyponatremia potassium treatment acute binding causes chronic gitelman hypotonic medications pathophysiology phosphate physiologic syndrome
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
Algorithm for Management ... Acute and Chronic Hyperkalemia ... Acute Hyperkalemia ... Chronic Hyperkalemia ... optimization) #Hyperkalemia
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... Lowers level of low-density ... increased risk of low ... #Table #Comparison
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Present (Uosm ≥100): Hypovolemia ... , Hypervolemia with ... differential #diagnosis #table ... #sodium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... alkalosis • Normal or low ... pressure Labs: • Hypokalemia ... pathophysiology #Hypokalemia
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... Hyponatremia: • Hypovolemia ... polydipsia • Hypervolemia ... diagnosis #causes #nephrology ... #sodium #low
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