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diagnosis nephrology management differential blood hematology hypokalemia product reactions treatment binding comparison kdigo low medications pharmacology pseudohyperkalemia rhabdomyolysis transfusion transfusions
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... increase dose as ... patients sensitive to high ... of aspiration #Potassium ... #pharmacology #table
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... complications such as ... treated with IV potassium ... urinary losses: • High ... #nephrology #low
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
KDIGO Treatment algorithm ... anuric ESKD or severe ... • Consider K+ binder ... #treatment #potassium ... #high #nephrology
Pseudohyperkalemia vs Reverse Hyperkalemia Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated. Pseudohyperkalemia: This
Reverse Hyperkalemia ... Causes: • Thrombocytosis ... potassium is high ... Causes: • Seen ... Potassium #Nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... fluid/Lactated ringers ... Monitor potassium ... per day until stable ... Dialysis for severe
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl < 0.7, high ... correcting serum potassium ... continued in most cases ... #nephrology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
High mortality. ... Presents as dyspnea ... Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... products contain potassium
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
High mortality. ... Presents as dyspnea ... Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... products contain potassium
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