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Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Dosing: Initial ... as necessary at 1- ... • Mechanism: Sodium-K ... level teaspoons) 1- ... #pharmacology #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... Elimination (see Table ... Redistribution Treatments ... 5-10U reg IV + 1- ... #potassium #nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... in 4 mL) - IV sodium ... mL/min) - Oral sodium ... Acute #Chronic #treatment ... #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... prevalence of 1- ... thiazide-sensitive sodium-chloride ... nephron → - ↑ K+ ... H+ secretion → Hypokalemia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... Na >1 is predictive ... : Hypovolemia, Hypervolemia ... #sodium #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
(correction of hypokalemia ... Oral sodium loading ... syndrome - Overnight 1- ... Causes #Screening #Workup ... #table
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... boluses 10 ml.kg-1 ... with dantrolene Hyperkalaemia ... hyperventilate, sodium ... Diagnosis #Management #Workup