1152 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma: ... mutated in one cell ... transformation of the cell ... mutated in all cells ... Complications: • Leukocoria
Leukocoria on Ocular Examination

#Leukocoria #Ocular #PhysicalExam #clinical #video #ophthalmology #retinoblastoma #pediatrics
Leukocoria on Ocular ... Examination #Leukocoria ... ophthalmology #retinoblastoma
Assessing and referring childhood cancers #Diagnosis #PrimaryCare #Peds #ChildhoodCancers #ClinicalFeatures #Lymphoma #Wilms #Leukemia #Retinoblastoma #BMJ
Wilms #Leukemia #Retinoblastoma
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can infiltrate ... disease • B cell ... AIHA • Pure red cell ... lymphoma • Hairy cell ... Smoldering adult T cell
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... activate naive CD4 T cells ... These T cells then ... induce B-cell class
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
The Cell Cycle ... The cell cycle is ... that controls cell ... factor (regulators) Retinoblastoma ... transcription factor #Rb #Retinoblastoma
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Involvement - B-cell ... CD10 - T-cell ... or λ), Smudge Cells ... - B-cell ... Thrombocytosis - T-cell
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... responses, and B cells ... antigen activates B cells ... binding to the B-cell ... binding to the T-cell
B/T Cell Development
This is a work in progress describing the maturation of B & T cells
B/T Cell Development ... maturation of B & T cells ... more to the T cells ... #lymph node #b-cell ... #t-cell
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
of ALL is of B-cell ... lymphadenopathy • Blast cells ... organs When Cancer Cells ... Hypogammaglobulinemia, smudge cells ... form of large cell