13 results
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... cardiac valve, vasculitis ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... morning • Effusion leukocyte ... Crystal induced (Gout ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Negative, ruling out ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... Vessels: Supply gut ... -> abdominal pain ... , testes -> pain ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Positive Coombs testing ... younger pts) Differential ... chills, flank pain ... #anemia #hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... swelling, significant pain ... Synovial Fluid Testing ... Intracellular (leukocyte ... #Comparison #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... , and low back pain ... #laboratory #workup ... #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Tophi - Gout ... Lyme disease, Vasculitis ... #differential # ... diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... pathognomonic laboratory ... Behcet disease) Differential ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology