6 results
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Serum levels of PTH ... - Calcium-sensing ... activating mutation - Parathyroid ... Chronic kidney disease ... #Diagnosis #Endocrinology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
production - Hyperparathyroidism ... Incr levels of parathyroid ... #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: ↑→PTH, ↑Calcium ... : ↑PTH, ↓→Calcium ... : ↑↑PTH, ↑Calcium ... #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... precipitates with calcium ... Imaging may show chondrocalcinosis ... Intracellular (leukocyte
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis ... : Calcium Pyrophosphate ... ) Deposition Disease ... #Symptoms #Pathophysiology ... #Diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... Hemochromatosis • Hyperparathyroidism ... culture used to diagnose ... Imaging may show chondrocalcinosis ... #Rheumatology #diagnosis