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diagnosis alp phosphatase algorithm biliary cholangitis cirrhosis elevation enzymes hepatocellular hyophosphatasia lfts liver low pbc primary transaminitis workup
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Enzymes (LFTs) - Causes ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline ... Transaminitis #diagnosis #differential ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Intestine - Other causes ... • Placenta • Leukocytes ... - Pruritis - Cholestasis ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • recurrent fractures ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Labs: • Alkaline ... bile ducts Differential ... diagnosis #workup #hepatology
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