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algorithm liver oncology phosphatase biliary cholangitis cirrhosis classification enzymes hepatitis hepatocellular hodgkins hyophosphatasia injury lfts lymphoma management mds myelodysplasia myelodysplastic
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Intestine - Other causes ... • Placenta • Leukocytes ... #Elevation #Differential ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Enzymes (LFTs) - Causes ... elevation > Alk ... + ULN ALT) / (alkaline ... #differential # ... hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Low Alkaline Phosphatase ... Most cases diagnosed ... of Low Alkaline ... Phosphatase: • Other causes ... #hepatology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... stone, Malignancy, PBC ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... Labs: • Alkaline ... obstruction • ALP ... #workup #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... Mild-to-moderate elevation ... from ischemia WBC ... count and differential ... #Workup #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... levels: realllly low ... about secondary causes ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... Out Secondary Causes ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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