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hepatology algorithm management blood rheumatology transaminitis aflp arterial ascites biliary chemistry cholangitis cirrhosis dermatology dili druginduced effusions embolism fatty function
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Differential Diagnosis ... Hepatopathy • Acute ... injury) • Ischemic ... ) • Non-hepatic ... Diagnosis #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... Wilson disease ... #Causes #Differential ... #Hepatology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes ... of Acute Liver ... Injury: • Hepatic ... #injury #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... disease: > 2 ... #chemistry #diagnosis ... #differential #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... for alternative causes ... disease, Hepatic ... dechallenge • Acute ... #Injury #Diagnosis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #Diagnosis #causes ... #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Alcoholic hepatitis ... fibrosis - Acute ... #diagnosis #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... acid metabolism products ... = nonspecific (nausea ... infiltration) Differential ... Hepatitis, Preeclampsia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Types: • Leukocyte ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
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