16 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... • Placenta • Leukocytes ... - Drugs - Pregnancy ... elevation DDX of Hepatic ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... for Transaminitis ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
more specific for hepatic ... + ULN ALT) / (alkaline ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... Pregnancy (AFLP) ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Diagnosis Framework ... Hepatopathy • Acute ... ) • Non-hepatic ... #Diagnosis #hepatology ... #transaminitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... ) Pathophysiology ... infiltration) Differential ... Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Hepatic vein: ... melanoma, myeloma • Pregnancy
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Diagnosis #Causes ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... • Cirrhosis/acute ... of pregnancy ... #hepatology