29 results
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Types: • Leukocyte ... Reaction (FNHTR ... Reaction (AHTR) ... proteins on plts, leukocytes
Estimated Incidence of Transfusion Reactions
Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence.
#Diagnosis
Reactions Graphical ... Depiction of transfusion ... reactions ordered ... #Diagnosis #Blood ... #Reactions #Events
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... proteins on plts, leukocytes ... in transfused blood ... @nickmmark #Blood
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... of high parity blood ... #Reactions #hematology ... #diagnosis #comparison
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Examples: Acute transfusion ... reaction, Haemolytic ... recruitment of leucocytes ... classification #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Crush injury • Blood ... transfusion • ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
shortly following a transfusion ... #Diagnosis #Transfusion ... #Reaction #TRALI ... #TACO #Comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Crush injury • Blood ... transfusion • ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Leukocytosis: The term 'leukocyte ... defined as white blood ... in peripheral blood ... Leukemoid reaction ... precursor cells to leukocytes
Receptor actions of sympathomimetic and dopaminergic agents.
Adrenaline (epinephrine) 
Noradrenaline (norepinephrine) 
Isoprenaline 
Dopamine 
Dopexamine 
Dobutamine 

#Pharmacology #Vasopressors
Receptor actions ... Dobutamine #Pharmacology ... Specificity #Dopamine #Comparison