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differential management rheumatology table causes classification hematology syndrome allergy blood hypersensitivity product taco trali treatment types vasculitis workup acute algorithm
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... S/sx: Fever, flank ... proteins on plts, leukocytes ... Sx include: fever ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... proteins on plts, leukocytes ... Sx include: fever ... #diagnosis #management
Differential Diagnosis - Noninfectious Causes of Fever CRITICAL DIAGNOSES: - Acute myocardial infarction - Pulmonary embolism or
Noninfectious Causes of Fever ... insufficiency - Transfusion ... reaction - Pulmonary ... - Drug fever ... Malignancy - Gout
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... explain symptoms • Fever ... pulmonary edema) • Fever ... #Reactions #hematology ... #diagnosis #comparison
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Anaphylaxis, Hay fever ... Examples: Acute transfusion ... recruitment of leucocytes ... classification #comparison
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
shortly following a transfusion ... #Diagnosis #Transfusion ... #Reaction #TRALI ... #TACO #Comparison
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
of Acute Onset Fever ... - Differential Diagnosis ... Iatrogenic: • Transfusion ... reaction • Malignant ... #Differential #Diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
A reaction to phagocytosed ... 12-24 Hours • Fever ... Intracellular (leukocyte ... #Comparison #rheumatology ... #Diagnosis
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Gout - Diagnosis ... A reaction to phagocytosed ... 12-24 Hours • Fever ... Intracellular (leukocyte ... severe allergic reactions
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
NINDS Diagnostic ... dysfunction, Absence of fever ... at onset • >50 Leukocytes ... polymorphonuclear leukocytes ... Features That Rule out
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