92 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Manifestations of Systemic ... Erythematosus (SLE) #Systemic ... Manifestations #Signs #Symptoms ... #Rheumatology # ... Diagnosis
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
disease by organ system ... Disease #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
the Mnemonic "no skin ... -6011359#5 #diagnosis ... #differential #symptoms ... #signs #dermatology ... #skin #skinrash
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... joints Nervous system ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... anti-Sc170): Diffuse skin ... BCM_InternalMed #Systemic ... Autoantibodies #diagnosis ... #rheumatology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... @AnnKumfer #Systemic ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... • Xerosis (dry skin ... #generalized #dermatology ... #Differential #Diagnosis
Urticaria (hives): Skin reaction that occurs in response to cold, food allergies, meds, environmental exposures, stings,
infections
Urticaria (hives): Skin ... associated with systemic ... symptoms. ... Clinical #Photo #Dermatology