Leukocyte urinalysis workup pediatrics fever diagnosis disease syndrome differential infectiousdiseases algorithm pth hemolytic dehydrogenase anemia

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Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology

Hemolysis - Differential Diagnosis Framework

1) Environment
- Fragmentation
- MAHA: TTP, HUS, DIC, HELLP

Hemolysis - Differential ... , Evans Syndrome ... Defects: Sickle cell anemia ... - Lactate Dehydrogenase ... - AST ↑ - Urinalysis

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Differential Diagnosis ... Symptoms: High fevers ... #hemolytic #anemia

Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout

Elevated Lactate Dehydrogenase ... (LDH) - Differential ... Diagnosis Framework ... anemia, PNH, immune ... myocarditis, rheumatic fever

TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A

hallmark for the disease ... Serum lactate dehydrogenase ... WBC count and differential ... a left shift Urinalysis ... #Workup #Hematology

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