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oncology chronic leukemia lupus sle systemic agglutinin arteritis classification cold cvid differential disease fungal gca giantcell hemeonc hodgkins hypogammaglobulinemia immunodeficiency
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Overview: • Most common ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... - most common presentation ... Diagnosis: • hemolytic ... #anemia #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... (75%): Anemia ( ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
edema, active urine ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... Kidney disease common ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... (NSHL) - (most common ... classification #hematology ... #oncology #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... Nodosa: • PAN most commonly ... ischemia • Skin: Erythematous ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
droppings • Most common ... • Rheumatologic ... : • Increased leukocyte ... count (mainly lymphocytes ... #Management #Infections
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