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oncology disease symptoms workup agglutinin aplastic arteritis behcet chronic classification erythematosus gca giantcell hemolysis hodgkins laboratory lupus lymphocytic lymphoma monoclonal
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... • Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA, Cold ... anemia, Thalassemias ... - Peripheral Blood ... Diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #oncology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... leukocytes. ... Tissue damage • Leukemia ... Degree of bandemia ... #WBC #CBC #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... virus (EBV) • Leukemia ... result from low blood ... #oncology #hematology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... tears, Ischemia, Leukemia ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... edema, active urine ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... Diagnosis = clinical ... systemic complaints- anemia ... them, but urgent rheumatology ... #Management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... count (CBC) • ... • Serum and urine ... #testing #Rheumatology
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