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diagnosis treatment differential hematology rheumatology neurology barre cppd gout guillain hepatology hepatopulmonary infectiousdiseases oncology workup 1 abscess algorithm anemia anesthesia
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... leukocytes. ... cultures, including blood ... predictive of a serious infection ... #pathophysiology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Irritable bowel syndrome ... Parasitic infections ... disease - Fecal leukocytes ... and occult blood ... Chronic #Diarrhea #management
Pathogenesis of meningitis Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
site-specific infections ... changes in the blood ... expression of more leukocyte ... cell (WBC) binding ... #Meningitis #Pathophysiology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... confirm DAH, r/o infection ... reveals increasing blood ... differential #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... APML #diagnosis #management
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
Intraoperative Sepsis ... ≥ 4mmol.l-1 if infection ... gas, lactate, FBC ... Discuss ongoing management ... Checklist #Diagnosis #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... proteins on plts, leukocytes ... • Infection - ... Infection occurs ... Transfusions #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... • ↓ WBC • ↓ ... result from low blood ... hematology #diagnosis #management
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... response preceding infection ... - NORMAL CSF WBC ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Diagnosis and Management ... Diarrhea (>3 BM/d) ± blood ... pain, Fever, ↑WBC ... Perforation) Pathophysiology
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