31 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure ( ... disease, liver ... Kidney Failure ... Injury (DILI) ... #Hepatology #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Injury (DILI) ... or symptoms of liver ... Drug #induced #Liver ... #algorithm #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Liver Injury: ... Liver Injury: ... Liver Injury:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Skin involvement, Kidney ... Alcohol-related liver ... dechallenge • Acute
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Liver Failure ( ... ALF): • Liver ... Hepatocellular Level ... chemistry #diagnosis #differential
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Liver Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... #Causes #Differential ... Incidence #Table #Failure
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Hepatopathy • Acute ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
liver failure ... Seizures Kidney ... abnormalities Liver ... lung injury, ... #liver #failure
Causes of Gallbladder Wall Thickening
Primary Wall Thickening:
1 . Acute calculous cholecystitis
2. Acute acalculous cholecystitis
3. Chronic cholecystitis
4.
Adenomyomatosis Secondary ... Systemic Processes: Liver ... failure, Renal ... failure, Heart failure ... Thickening #Causes #differential
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... cardiorenal syndrome) • Liver ... failure (a.k.a. ... #Kidney #Injury