4 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... Treatment: - If febrile ... dysrhythmias, seizures ... diagnosis #management #hematology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cardiac arrhythmias, seizures ... hemorrhagic rash; symptoms ... causes CNS and hematologic ... Immunization #peds #pediatrics ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Attempt if high risk ... Rare: DAH, acute febrile ... Diagnosis: >3 symptoms ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Risk factors 3. ... elevated protein level ... persistent altered level