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diagnosis differential causes lfts treatment ascites transaminitis gastroenterology acute cholangitis chronic dili hbv hepatitisb hepatocellular primary saag summary abscess aclf
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... (Drug-induced liver ... injury) • Ischemic ... ) • Non-hepatic
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... support, or liver ... Injury (DILI) ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... Artery: Shock Liver ... Causes #Acute #algorithm ... #hepatology
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
End Stage Liver ... Syndrom (HRS) • Liver ... SBP) #ESLD #Liver ... #diagnosis #management ... #summary #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Alcohol-related liver ... cholangitis Consider liver ... #DrugInduced #Liver ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Injury: • Hepatic ... : < 1 • Cirrhosis ... #injury #hepatitis ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... Disease, Fulminant Hepatic ... Differential #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Clues to non-cirrhotic ... /acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Diagnosis #causes #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Check Acute viral hepatitis ... replaced by non-hepatic ... : < 1 • Cirrhosis ... #differential #Hepatology
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