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diagnosis hematology management oncology activation aplastic arthritis cell chronic classification cll differential disease hemeonc hemolytic hemophagocytic hlh hodgkins incomplete kawasaki
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... bartonella (oroya fever ... ARUPLabs #Hemolytic #Anemia ... #workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... with leukopenia, anemia ... Treatment: • Corticosteroids
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... recurrent infections/fevers ... index < 2 • EPO Level ... Treatment:
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
old on day ≥7 of fever ... Albumin ≤3.0 g/dL, anemia ... echo is positive, treatment ... within 10 d of fever ... Diagnosis #Peds #Pediatrics
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary Clinical ... active ROM +/- fever ... viral arthritis Workup ... arthritis diagnosis Treatment ... 90% sensitive in pediatrics
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... microglobulin Treatment ... Leukemia #diagnosis #workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Characteristics: Persistent fever ... Clinical Presentation ... Persistent high fever ... - Cytopenias (anemia ... Fever b.
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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