171 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... DILI and Type of Liver ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Drugs that Cause Fever
Most commonly:
Amphotericin B, Antihistamines, Asparaginase, Barbiturates, Bleomycin sulfate, Methyldopa, Penicillins, Phenytoin sodium, Procainamide,
Drugs that Cause ... Fever Most commonly ... hydrochloride #Drug #Fever ... #causes #differential ... #diagnosis #pharmacology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - Management ... Stabilization Concern for Liver ... Consult GI ± EGD Causes ... GAVE (idiopathic, liver ... Differential #Diagnosis #management
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... m2 • Severe liver ... e.g. diarrhea, nausea ... #Metformin #Pharmacology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
should be TS and SF level ... out additional causes ... evaluation for other causes ... If other causes ... algorithm #diagnosis #management
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Aims to reduce level ... Disease #Treatment #management ... #pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Diagnosis and Management ... no respiratory cause ... Glucose, Salicylate level ... Toxic Salicylate Level ... : 150mg/kg Management
OPIOID SWITCHING AND TAPERING.

Long term opioid use results in physical (and potentially psychological) dependence. Opioids should
include: chills, fever ... sweating, anxiety, nausea ... tapering #switching #pharmacology ... #conversion #management
Antibiotic Therapy for Spontaneous Bacterial Peritonitis  (SBP)

- Standard therapy 
- Uncomplicated SBp• 
- Nosocomial SBP
hypersensitivity - Advanced liver ... renal failure #Management ... Antibiotic #Regimen #Pharmacology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... rapidly fatal • Causes ... Identify underlying cause ... Cooling blankets can cause ... comparison #diagnosis #management