9 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Systemic Lupus ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... Algorithm #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involvement Differential ... • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
diseases LIP: lymphoid ... SLE : systemic lupus ... CTILD #Diagnosis #Differential ... #Comparison #Table ... #Pulmonary #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Workup: • Full ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Angioimmunoblastic T-cell lymphoma ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... spondyloarthropathies, lupus ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
bone marrow at a level ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology