26 results
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Clinical Manifestations ... sounds, RUQ pain • Dermatologic ... Diaphresis, flushing • CNS ... : Tachycardia, Fever ... spectrum #signs #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
initiation of smoking; Fever ... brown sputum, fever ... , wt loss; CV, CNS ... Travel hx, food hx; Fever ... #table #eosinophilia
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Diagnosis Algorithm ... papilledema • Horner syndrome ... and signs (e.g., fever ... brain lesion • CNS ... #neurology #PHANTOMS
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... mountain spotted fever ... #Diagnosis #hematology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Headache • Fever ... • Common clinical ... meningeal signs (fever ... #diagnosis #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... • Symptoms: Fever ... • Symptoms: Fever ... #Infections #differential
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
symptoms, fever ... ) • Headache, fever ... Meningitis: • Fever ... #Tuberculosis #diagnosis ... #differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Diagnosis Framework ... RBCs, muscle, liver ... elevated serum LDH level ... Periodic paralyses CNS ... myocarditis, rheumatic fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... following: • Fever ... lymph node, or liver ... management #treatment #hematology