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diagnosis rheumatology hematology oncology arthritis causes hodgkins physicalexam approach autoimmune classification comparison effusions erythematosus extremity inflammatory jointpain knee leg leukemia
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Pain - Differential ... Genitourinary Infection ... • Rheumatic Fever ... • Rheumatic Fever ... Inflammatory #JointPain #MSK
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... infection. ... #Joint #Pain #MSK ... approach #workup #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Alcohol-induced pain ... : Pain in involved ... #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Rheumatic fever ... streptococci (rheumatic fever ... #pain #Differential ... #Diagnosis #MSK
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... : • Infection: ... entrapment • Infections ... - Fever/chills ... lower #extremity #msk
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Knee Effusions - Differential ... Fever/Chills/Joint ... pain/Night sweats ... Acute rheumatic fever ... #diagnosis #msk
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... , fever, joint pain ... , bleeding, infections ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... classification #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... fibromyalgia) • Infections ... pain • Swan neck ... to: Arthritis, Fever
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Tenderness → Consider infectious ... Overlap Syndrome: Fever ... , joint pain and ... ANTI-SYNTHETASE SYNDROME: • Fever
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