11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... initiation • Differential ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Actively maintained fever ... CAUSES OF HYPERTHERMIA ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management ... #Workup
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Red Flags: • Fever ... deficiency Work ... #dermatology #physicalexam
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... and petechiae Causes ... Aplastic #Anemia #oncology ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Fever >38.5 2. ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
Travel History - Clues to Infectious Disease Diagnosis in a Traveler 
 • Where did you
Travel History - Clues ... Rabies, cat scratch fever ... Commercial sex worker ... HPI #Interview #InfectiousDiseases ... #Infections #differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... • Symptoms: Fever ... • Symptoms: Fever ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... blood count with differential ... #oncology