14 results
diagnosis hematology algorithm causes hodgkins leukemia lymphoma management rash bandemia cbc cell cellulitis chronic classification clinical comparison differentiation disorders gap
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Headaches, bone pain, fever ... - infiltrates (anemia ... smear: Blasts APML ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... • Neutropenia, anemia ... Transform to DLBCL, PML ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... bartonella (oroya fever ... Diagnosis #Algorithm #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Subacute-Acute: • Common: fever ... initiation • Differential ... Differentiation #Syndrome #APML ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
All oysters at Chesapeake ... Rapid onset of fever ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... rash #cellulitis #dermatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... Neutrophil (Normal) Differential ... tachycardia or fever ... #differential # ... neutrophil #WBC #CBC #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Red Flags: • Fever ... deficiency Work ... • Abdominal ultrasound ... Algorithm #Causes #dermatology
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