31 results
diagnosis treatment hematology rheumatology differential oncology pulmonary signs causes fungal hemophagocytic infections infectiousdiseases inflammatory lung lymphohistiocytosis neurology abscess acromegaly activation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... syndromes Clinical ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... signs and symptoms ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Inflammatory Multisystem Syndrome ... infection (PIMS-TS) Clinical ... features all: fever ... #PIMSTS #covid19 ... diagnosis #Signs #Symptoms
Summary of Infections in which Steroids play a role in treatment • TB meningitis • TB
Summary of Infections ... pneumonia • COVID ... Severe typhoid fever ... • Ramsay Hunt syndrome ... Indications #infections #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Summary Epidemiology ... renal failure Clinical ... General: fever, ... : ACUTE, fever, ... presentation with fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... - 80% have fever ... : • Pathophysiology ... TLS #diagnosis #management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Summary Clinical ... night sweats, fever ... Budd Chiari syndrome ... Symptoms of metastatic ... #Summary
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... cystitis, may have fever ... infection, such as fever ... Pathophysiology:
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... index < 2 • EPO Level ... • Improve the symptoms ... hematology #diagnosis #management
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