108 results
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Findings • ADEM -> Fever ... SOB, fatigue, fever ... N/V, elevated liver ... signs #symptoms #pathophysiology
Differential Diagnosis - Fever of Unknown Origin (FUO)

IMADE mnemonic:
 • Infection
 • Malignancy
 • Autoimmune (Rheumatologic)
Differential Diagnosis - Fever ... • Autoimmune (Rheumatologic ... udaygulati #FUO #Fever
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
GCA is almost never ... /Symptoms: - Fever ... Temporal #Arteritis #Pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... (2.4 vs. 1) • Fewer ... 35% vs. 24%) • Fewer ... Benefits #SickleCell #pathophysiology ... #pharmacology
Pathophysiology of Subendocardial and transmural ischemia on ECG

#Pathophysiology #Subendocardial #Transmural #Ischemia #ECG #EKG #Cardiology

** GrepMed Recommended
Pathophysiology ... ischemia on ECG #Pathophysiology ... EKG Book You'll Ever
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
gout #uricacid #pathophysiology ... #pharmacology # ... rheumatology
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen ... Pathophysiology ... production → Fever ... #Fever #Pathophysiology
Temporal (Giant cell) Arteritis 
Risk Factors:
 • Age (almost never occurs before age 50) 
Clinical:
 •
• Age (almost never ... Arteritis #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Rheumatology