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diagnosis oncology syndrome adult aosd apml classification differentiation disease evaluation hodgkins hypothermia leukostasis lymphoma lysis onset perioperative preop preoperative protocol
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... Treatment: - If febrile ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... common • Imaging: CXR ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Serum Copper • Chest ... X-ray (Mediastinal ... classification #hematology ... #oncology #management
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... event, follow ACC algorithm ... change CV risk Chest ... X-ray: • Not ... medical and surgical management
Hypothermia - Protocol for ED CORE TEMP < 34º INITIAL THERAPY • Remove wet garments • Avoid rough
ECG • ABG • Chest ... Xray MILD-MODERATE ... IV) • Rapid - Level ... Hypothermia #Protocol #management ... #treatment #algorithm
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