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hematology management differential blood hemophagocytic lymphohistiocytosis product rash reactions cardiology erythematous hemeonc murmurs nikolsky petechiae petechial physicalexam systolic transfusion transfusions
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... acute or subacute febrile ... following: • Fever ... lymph node, or liver ... management #treatment #hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
or absence of fever ... syndrome (SSS) in infants ... If fever is present ... #Diagnosis #Dermatology ... #Nikolsky #Febrile
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Pregnancy • Fever ... • Rheumatic Fever ... • Rheumatic Fever ... • Rheumatic Fever ... #Algorithm #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Red Flags: • Fever ... medication Febrile ... #Algorithm #Causes ... #dermatology #physicalexam
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
in febrile illness ... Characteristics: Persistent fever ... Onset: Usually in infancy ... Persistent high fever ... Fever b.
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #Transfusion #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #Transfusions #diagnosis
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