12 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... • Autoimmune diseases ... Drugs, Unknown cause ... Treatment: •
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... #oncology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... • Metabolic syndrome ... 12-24 Hours • Fever ... #Gout #Comparison ... #rheumatology #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Fever >38.5 2. ... : symptomatic treatment ... • Severe disease ... SinaiBmoreIMRes #DRESS #Syndrome
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... acute neck pain, fever ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis