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diagnosis management differential hematology oncology dermatology hemophagocytic lymphohistiocytosis hemeonc infant peds product reactions abscess agep anemia anesthesia anesthesiology antibiotics aplastic
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Treatment: •
Clinical Algorithm for Emergency Department Evaluation and Management of UTI in Febrile Infants and Young Children Urinary
Clinical Algorithm ... Management of UTI in Febrile ... Urinary tract infection ... department with fever ... #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... can mimic common infections ... acute or subacute febrile ... following: • Fever ... : • Infection
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... serious bacterial infections ... an infant with fever ... #Peds #Febrile ... Stratification #Fever
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... : • Complete blood
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
confusion and fever ... Fever recurs over ... increases during febrile ... Infectious Diseases ... microscopy #pathology #clinical
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
- Management Algorithm ... purulence Obtain blood ... • Persistent fever ... • Persistent fever ... Hernodynamically stable after treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... consideration in febrile ... Characteristics: Persistent fever ... Persistent high fever ... Fever b.
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... Infection - Infection
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... donors (due to anti-HLA ... Sx include: fever
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