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diagnosis hematology management reactions blood product transfusion comparison fatty hemophagocytic hlh lymphohistiocytosis macrophage mas obgyn obstetrics pathophysiology pregnancy rheumatology syndrome
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... , vomiting, abdominal ... Transfer to a liver ... #Fatty #Liver #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
sequestration and activation ... without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... eruptions, diarrhea, liver ... diagnosis #management #hematology
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