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diagnosis differential hematology infectiousdiseases pulmonary syndrome algorithm oncology abscess cardiology cirrhosis classification disease endocarditis failure gastroenterology hemophagocytic hepatitis hepatopulmonary hlh
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... Brain Failure Lung ... Coagulation Failure Infections ... Failure #Cirrhosis #Hepatology
Liver Abscess • Pyogenic abscess, accounts for 80% of abscess. • Amebic abscess due to Entamoeba histolytica, accounts for 10%. • Fungal
Liver Abscess • ... 50% of solitary liver ... occur in the right Liver ... • Fever in 90% ... cm Continuous fever
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... , vomiting, abdominal ... malaise) → Acute liver ... Transfer to a liver
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... (daptomycin in lungs ... • Secondary to Treatment ... SJS, DIHS, drug fever ... thrombophlebitis), HAP, Blood
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... : • 80% have fever ... anemia • Sputum/Blood ... Intervention: - Fevers ... #management #treatment
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Chest pain, cough, bloody ... lymphadenopathy, • Abdominal ... factor • May cause ... #Infections #HIV
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Clinical: fever ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Injury: • Infectious ... CA, small cell lung ... intestines, white blood ... diagnosis #algorithm #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... disease • Liver ... Low serum IgG level ... DDX - Other causes ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
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