40 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... - Nonremitting fever ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology ... #Rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... symptoms, elevated liver ... is >1,000 μg/L, liver ... A liver biopsy can ... of liver disease
Liver Abscess
•	Pyogenic abscess, accounts for 80% of abscess.
•	Amebic abscess due to Entamoeba histolytica, accounts for 10%.
•	Fungal
Liver Abscess • ... 50% of solitary liver ... occur in the right Liver ... • Fever in 90% ... cm Continuous fever
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiency • Liver ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... , vomiting, abdominal ... malaise) → Acute liver ... Transfer to a liver
Pneumoperitoneum from perforated duodenal ulcer on RUQ POCUS

Male with severe RUQ abdominal pain. Answer in thread.
duodenal ulcer on RUQ POCUS ... with severe RUQ abdominal ... anterior to the liver ... #clinical #ultrasound ... #Abdominal
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
gas on hepatic ultrasound ... ileus), intra-abdominal ... variety of other causes ... #hepatology #liver ... #pocus #clinical
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Daily high spiking fever ... - Fever spikes ... Fever of at least ... /splenomegaly, liver ... AOSD #diagnosis #rheumatology