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diagnosis differential hematology abnormal acute aflp anemia aplastic ascites common cvid enzymes hemeonc hemophagocytic hepatomegaly hlh hypogammaglobulinemia hyponatremia immunodeficiency immunology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #Liver #Pregnancy
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty ... Liver • Cysts ... • Budd-Chiari Syndrome ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pancreatic cancer ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... Artery: Shock Liver ... #Acute #algorithm ... #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... presence of metabolic syndrome ... non-alcoholic fatty ... #LFTs #Abnormal ... #Algorithm #Hepatology
Common Malignancies That Cause Ascites The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
carcinomatosis or liver ... Liver Cancer (Hepatocellular ... peritoneum or liver ... malnutrition or liver ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... Lymphoma or other cancers ... gastric and breast cancer ... Low serum IgG level ... DDX - Other causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... index < 2 • EPO Level ... Marrow hypoplasia/fatty ... Aplastic #Anemia #oncology ... #management
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
in Cancer UOsm ... capillary leak syndrome ... amyloidosis) • Liver ... chemotherapy, nausea ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... it is often a cancer ... - Elevated liver ... #Hematology #HemeOnc
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