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diagnosis hematology differential causes anemia activation aplastic apml bleeding classification common cvid differentiation disorders elevatedmcv enuresis failuretothrive ftt hemophagocytic history
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
NON-WEIGHT BEARING CHILD ... Rheumatology ... #Limping #NWB #Algorithm ... #Pathway #Child ... #Peds #Pediatrics
Diagnostic algorithm for a child or adolescent with suspected pulmonary hypertension. CHD, congenital heart disease; CPET,
Diagnostic algorithm ... for a child or ... ; LFT, liver function ... #Diagnosis #Peds ... #Pediatrics #Pulmonary
Causes of Enuresis - Differential Diagnosis Algorithm Primary Nocturnal Enuresis (Urinary Control Never Achieved) • Delayed Maturation
Urinary Control Never ... Behavioural/Psychogenic (Child ... Non-neurogenic (Hinman Syndrome ... #Causes #Peds # ... Pediatrics
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... syndromes Clinical ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... • Pancreatic Disease ... Myelodysplastic Syndromes ... Disease #Macrocytic ... #Causes #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... Low serum IgG level ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Causes of Failure to Thrive - Differential Diagnosis Algorithm Adequate Calorie Consumption - Increased Losses:
• Liver Disease ... Disorders • Syndromes ... Disturbed Parent-Child ... #Causes #Peds # ... Pediatrics
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
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