18 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
F • 3 peaks: 1) ... Aplastic Anemia Clinical ... index < 2 • EPO Level ... result from low blood ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL-1 ... syndromes Clinical ... is the main clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... diffusion-perfusion defect (Type 1) ... shunt (Type 2) Clinical ... passage • Arterial blood ... #treatment #hepatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Actively maintained fever ... anaphylaxis (→ 3-1) ... • Intracranial blood ... Checklist #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... symptoms, or> 1 ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... to 8 years Clinical ... Low serum IgG level ... : • Nephrotic syndrome
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
RBCs (stored at 4C ... 100,000,000, HCV 1 ... 2,000,000, HTLV 1 ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
RBCs (stored at 4C ... 100,000,000, HCV 1 ... 2,000,000, HTLV 1 ... Transfusion #diagnosis #management ... #hematology #reactions
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Dermatomyositis Clinical ... Muscle swelling - Fever ... UA positive for blood ... Differential #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
PRES Diagnosis: 1. ... elevated protein level ... elevated white blood ... persistent altered level ... #diagnosis #management