20 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint ... Inhibitor Toxicity ... Complications and Treatment ... #SideEffects #Table ... #Diagnosis #Pharmacology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... - Summary Clinical ... , immune-mediated ... IU/I • SAMS clinical ... Statin #muscle #toxicity
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the Treatment ... highlighted circle= clinical ... trial Ever Arias ... #COVID19 #Pharmacology ... #Table #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... HCV - HIV • Immune ... index < 2 • EPO Level ... aplastic anemia Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... underlying genetic immune ... • Bicytopenia Treatment ... diagnosis #management #treatment
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... decrease in HIV-1 RNA level ... noncompliance • Clinical ... initiation Clinical ... Drug reaction/ART toxicity
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Medication/Drug toxicity ... elevated protein level ... persistent altered level ... epilepticus Treatment ... underlying cause • Treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
activity → local immune ... renal failure Clinical ... Self-limiting, chronic but stable ... Specific sarcoidosis syndromes ... • Heerfordt syndrome